一种新的方法来提高可植入医疗器械的射频安全性,使用在3.0 T MRI 时的感应合
Bu S Park1, Joshua W Guag2, Hongbae Jeong2
1Division of Cellular and Gene Therapies (DCGT), OTAT, CBER, Food and Drug Administration (FDA), Silver Spring, MD, USA. bu.park@fda.hhs.gov.
Magma (New York, N.Y.)
|August 11, 2023
概括
一个新的二次共振器 (SR) 减少射频 (RF) 场,特定吸收率 (SAR),并在MRI扫描期间温度升高. 这种方法增强了患者在身体线圈附近植入医疗设备的安全性.
科学领域:
- 医学物理 医学物理
- 生物医学工程 生物医学工程
- 磁共振成像技术 磁共振成像技术
背景情况:
- 植入式医疗器械 (IMD) 在MRI过程中存在射频安全风险.
- 在IMD附近的加热是当它们在体卷内但在成像区域之外时令人担忧的.
研究的目的:
- 为了减少电场,特定吸收率 (SAR) 和MRI期间的温度变化.
- 为了提高位于机身线圈内但在成像区域之外的IMD的射频安全性.
主要方法:
- 使用ASTM幻象和人类模型进行数值模拟 (Ella,Duke).
- 设计和测试具有特定尺寸的圆形二次共振器 (SR).
- 使用3TMRI系统,电磁场探针和ASTM幻影仪进行实验验证.
主要成果:
- 在ASTM幻影中,SR降低了B1+和SAR1g的15.2%和5.85%.
- 在一个带有铜棒的Ella模型中,SR降低了ΔdB1+和ΔdSAR1g高达56.7%和57.5%.
- 由SR产生的相反的磁场部分屏蔽了样品.
结论:
- 一种新的SR方法有效地减轻了3.0T的诱导RF加热风险.
- 通过减少射频场沉积,SR提高了IMD的安全性.
- 数字模拟和实验证实了SR在各种条件下的有效性.
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