SARS-CoV-2 在水和废水中的持久性
Aaron Bivins1,2, Justin Greaves1, Robert Fischer3
1Department of Civil & Environmental Engineering & Earth Sciences, University of Notre Dame, Notre Dame, Indiana 46556, United States.
概括
传染性SARS-CoV-2在室温下在废水中维持几天的生命力,但在热量下迅速失活. 在环境中检测SARS-CoV-2RNA并不能证实传染性病毒存在.
科学领域:
- 环境科学 环境科学
- 病毒学 病毒学
- 公共卫生 公共卫生
背景情况:
- 严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) RNA经常在便中检测到.
- 人们对废水中的传染性SARS-CoV-2存在担忧.
- 在水/废水中SARS-CoV-2的无活化是很少理解的.
研究的目的:
- 确定SARS-CoV-2在水和废水中的持久性.
- 评估传染性SARS-CoV-2的无活化特征.
- 在传染性病毒和RNA信号持久性之间进行区分.
主要方法:
- 随着时间的推移,在自来水和废水中量化了可行的SARS-CoV-2和RNA信号.
- 在室温和高温 (50°C,70°C) 中评估失活.
- 对于传染性病毒,计算了90%的减少时间 (T90).
主要成果:
- 在室温下废水和自来水中的可活性SARS-CoV-2的T90为1.5天和1.7天.
- 高病毒标位 (10^5 TCID50 mL-1) 持续感染7天.
- 在废水中,T90在50°C下降到15分钟,在70°C下降到2分钟.
- SARS-CoV-2 RNA 比传染性病毒更持久.
结论:
- 传染性SARS-CoV-2可以在废水环境中持续存在.
- 热能有效地使废水中的SARS-CoV-2无活化.
- 仅仅环境RNA检测不足以表明感染风险.
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