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干热作为N95呼吸器重复使用的净化方法
Chamteut Oh1, Elbashir Araud2, Joseph V Puthussery1
1Department of Civil and Environmental Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
概括
干热处理有效地去污染N95呼吸器,使病毒失活并保持完整性,以便重复使用. 这种使用电的可访问方法为短缺期间的呼吸器清除污染提供了可行的解决方案.
科学领域:
- 病毒学 病毒学
- 公共卫生 公共卫生
- 材料科学 材料科学 材料科学
背景情况:
- 像COVID-19这样的流行病可能导致N95呼吸器的严重短缺.
- 由于供应链中断,医疗保健提供者可能需要重复使用呼吸器.
研究的目的:
- 评估干热处理对于安全的N95呼吸器清除污染和重复使用.
- 评估干热对常见呼吸道病毒的疗效及其对呼吸器完整性的影响.
主要方法:
- N95呼吸器 (1860,3M) 用电进行干热处理 (100°C,5%RH,50分钟).
- 使用图兰病毒 (TV),轮状病毒 (RV),腺病毒 (AdV) 和传染性胃肠炎病毒 (TGEV) 测试病毒失活.
- 呼吸器完整性通过颗粒过效率和20个脱污周期后的定量适合性测试来评估.
主要成果:
- 干热处理实现了显著的病毒日志减少:TV (>5.2),RV (>6.6),AdV (>4.0) 和TGEV (>4.7).
- 在20个循环后,N95呼吸器的完整性,包括颗粒过效率和适合性测试,仍然没有妥协.
- 电方法在50分钟内保持100°C,这对于有效的清除污染至关重要.
结论:
- 使用电 (米,即食,烤箱) 的干热消毒是N95呼吸器重复使用的有效和可访问的方法.
- 建议在100°C下保持50分钟才能成功消毒.
- 这种方法提供了一种实际的解决方案,可以在公共卫生紧急情况下扩大呼吸器的可用性.
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