接种抗Covid-19疫苗后的发烧和呼吸障碍:一个具有挑战性的诊断
Mariangela Palladino1, Martina Del Vecchio2, Simone Farroni2
1Department of Translational and Precision Medicine, Sapienza University of Rome, Viale Dell'Università 37, 00185, Rome, Italy. mariangelapalladino@tiscali.it.
Internal and emergency medicine
|August 11, 2023
概括
一个罕见的成人发病史蒂尔病 (AOSD) 在COVID-19疫苗接种后发展. 在评估疫苗的风险和益处时,医生应该考虑这种潜在的不良事件.
科学领域:
- 免疫学 免疫学 免疫学
- 疫苗学 疫苗学 疫苗学
- 类风湿病学 类风湿病学
背景情况:
- 关于COVID-19疫苗的长期安全性的数据有限.
- 自身免疫性疾病可以由各种刺激引发,包括疫苗接种.
研究的目的:
- 在接种COVID-19疫苗后报告成人发病斯蒂尔病 (AOSD) 病例.
- 突出COVID-19疫苗接种与自身免疫性疾病的出现之间的潜在关联.
主要方法:
- 病例报告详细介绍了一名患者出现了暗示AOSD的症状.
- 临床评估,包括症状评估和实验室结果.
- 与COVID-19疫苗接种有关的症状出现的时间分析.
主要成果:
- 一名患者在接种COVID-19疫苗的第一剂后几周内出现了新发成人发病的斯蒂尔病 (AOSD).
- 患者出现呼吸不全和双侧胀,与AOSD诊断一致.
- 在COVID-19疫苗接种和AOSD发病之间观察到一个时间关系.
结论:
- 接种COVID-19疫苗可能与成人开始的斯蒂尔病 (AOSD) 的出现有关.
- 医生应考虑在出现新发自免疫性疾病的患者中与疫苗相关的不良事件.
- 对个体患者来说,仔细评估COVID-19疫苗接种的益处风险关系至关重要.
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