胃口,缺氧和急性山病:一个10小时的Normobaric缺氧室研究
Holly Barclay1,2, Saptarshi Mukerji3, Bengt Kayser4
1Nelson Hospital, Te Whatu Ora-Health New Zealand, Ministry of Health, Nelson, New Zealand.
High altitude medicine & biology
|August 11, 2023
概括
低氧,或低氧,抑制了食欲,减少了对甜食,和脂肪食物的渴望,在10小时的研究中. 急性山病 (AMS) 进一步增加了食欲丧失.
科学领域:
- 高空疾病研究 高空疾病研究
- 人类生理学 人类生理学
- 营养科学 营养科学
背景情况:
- 低氧和急性山病 (AMS) 对食欲和食物偏好的影响,特别是在低氧暴露的早期阶段,仍然不清楚.
- 了解这些影响对于高海拔地区的健康管理至关重要.
研究的目的:
- 为了研究10小时的normobaric缺氧暴露对健康个体的食欲和食物偏好的影响.
- 确定AMS症状与食欲和食物选择的变化之间的关系.
主要方法:
- 27名健康参与者 (13名女性) 在随机的单盲交叉设计中接受了10小时的normobaric normoxia (FiO2:0.21) 和normobaric hypoxia (FiO2:0.12,相当于5,000m) 的暴露.
- 食欲 (饥饿,满意度,腹,感知食欲,失去食欲),食物偏好 (甜,,,脂肪) 和AMS (路易斯湖得分) 通过问卷进行了评估.
- 分析了数据,以比较正常氧和缺氧之间的反应,并将AMS严重程度与食欲变化相关联.
主要成果:
- 低氧显著降低饥饿感和整体食欲,与正常氧相比 (分别p=0.040和p<0.001).
- 这种食欲下降与对甜食,食和脂肪食物的欲望下降有关 (p<0.05对所有人).
- 肌痛性硬化症的严重程度与对甜食 (R=-0.438,p=0.032) 和食 (R=-0.460,p=0.024) 的渴望减少以及对食欲的更大丧失 (R=-0.619,p=0.018) 相相关.
结论:
- 急性暴露于缺氧迅速抑制健康个体的食欲.
- 急性山病的发展加剧了食欲抑制和厌食症.
- 这些发现对高海拔探险和旅行期间的营养支持和幸福感有影响.
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