新兴的生物打印用于伤口愈合
Zijian Wang1,2, Xiao Liang1, Guanyi Wang2
1Department of Biomedical Engineering, Hubei Province Key Laboratory of Allergy and Immune Related Disease, TaiKang Medical School (School of Basic Medical Sciences), Wuhan University, Wuhan, 430071, China.
Advanced materials (Deerfield Beach, Fla.)
|August 11, 2023
概括
生物打印可以创建具有定制结构和功能的智能伤口包裹,以加速皮肤再生. 本综述涵盖了生物打印伤口愈合器件的技术,材料和未来方向.
科学领域:
- 生物医学工程 生物医学工程
- 材料科学 材料科学 材料科学
- 再生医学是一种再生医学.
背景情况:
- 生物打印是制造先进生物医疗设备的关键技术.
- 使用生物打印制造的智能伤口带提供了定制的结构和功能,用于增强皮肤再生.
研究的目的:
- 为智能伤口带提供生物打印技术的全面审查.
- 强调生物打印在控制生物结构和生物功能的作用,用于治疗伤口的应用.
主要方法:
- 生物打印技术和设备的概述.
- 深入讨论聚合物基油墨,改造策略,添加剂,性能和应用.
- 修改策略的分类,包括化学合成,物理混合,同轴,多材料,吸收,固定和细胞杂交.
主要成果:
- 生物打印允许精确控制伤口包裹的设计,匹配伤口位置的几何形状并促进再生.
- 各种修改策略可以增强生物打印设备的功能.
- 新兴领域包括4D生物打印,人工智能辅助生物打印和现场生物打印.
结论:
- 生物打印对于开发先进的智能伤口包裹至关重要.
- 跨学科的方法和新兴技术有望在生物打印伤口愈合方面取得重大进展.
- 应对当前的挑战对于这一领域的未来前景至关重要.
相关概念视频
Overview of Regeneration and Repair
Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
All animals have varying degrees of...
Regeneration
All animals have varying degrees of...
Phases of Wound Repair
Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...


