生物医学研究中的不当行为:元分析和系统审查
Ritu Phogat1, Bhadravathi Cheluvaiah Manjunath1, Bhavna Sabbarwal1
1Department of Public Health Dentistry Post Graduate Institute of Dental Sciences, Rohtak, India.
科学不当行为,包括抄袭和数据捏造,在生物医学研究中非常普遍. 非自我报告的研究显示,与自我报告的研究相比,不当行为率显著更高.
科学领域:
- 生物医学研究伦理学
- 科学完整性 科学完整性
- 出版伦理出版的伦理.
背景情况:
- 研究不当行为对科学发现的完整性构成重大威胁.
- 了解不当行为的普遍性对于实施有效的预防措施至关重要.
- 之前的研究在方法上有所不同,并报告了不当行为率.
研究的目的:
- 评估生物医学研究中科学不当行为的性质和普遍性.
- 为了比较自我报告和非自我报告的研究之间的不当行为率.
- 提供全球研究不当行为的综合估计.
主要方法:
- 使用PubMed Central,PubMed和谷歌学者进行了全面的文献审查.
- 与科学不当行为相关的MeSH术语和关键词被用于布尔式搜索.
- 16篇选定的文章使用Open Meta Analyst软件进行了元分析.
主要成果:
- 抄袭,数据编造和伪造是审查文章中常见的发现.
- 抄袭的流行率为4.2% (自我报告) 和27.9% (非自我报告).
- 数据伪造率为4.5% (自报) 和21.7% (非自报);伪造率为9.7% (自报) 和33.4% (非自报).
结论:
- 生物医学研究显示出令人震惊的不当行为率,特别是在非自我报告的研究中.
- 非自我报告的研究表明,不当行为比自我报告的研究更为普遍.
- 调查结果强调,迫切需要加强生物医学出版物的监督和伦理标准.
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