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Updated: Jul 19, 2025

Development of an Ethanol-induced Fibrotic Liver Model in Zebrafish to Study Progenitor Cell-mediated Hepatocyte Regeneration
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FGF9招募β-catenin来增加肝脏ECM合成和促进NASH驱动的HCC

Lei Zhang1,2, Qing Zhang1, Da Teng3

  • 1Department of Biochemistry and Molecular Biology, Metabolic Disease Research Center, School of Basic Medicine, Anhui Medical University, 230032, Hefei, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|August 11, 2023
PubMed
概括

纤维细胞生长因子9 (FGF9) 通过增加细胞外基质 (ECM) 沉积,驱动非酒精性脂肪肝炎 (NASH) 相关的肝癌. 降低FGF9水平减轻了NASH驱动的肝细胞癌 (HCC) 模型中的瘤生长.

关键词:
FGF9 联邦政府财政基金纳什·纳什 (Nash Nash) 是一个名为纳什的城市.细胞外矩阵是细胞外矩阵.肝癌 肝癌 是一种肝癌.这是一种β-catenin.

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