二十四小时眼内压力在慢性初级角度关闭疾病
Wasu Supakontanasan1, Yanin Suwan1, Suthaphat Nilphatanakorn1
1Department of Ophthalmology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok.
Journal of glaucoma
|August 11, 2023
概括
主角闭眼光大眼 (Primary angle closure glaucoma) 显示了24小时内眼压 (IOP) 波动的最高值. 周围前侧突的程度与主要角关闭性疾病中的IOP模式相关,即使是正常的IOP. 这突显了视角关闭疾病中的IOP变异性.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼研究研究 玻璃眼研究
- 眼内压力动态 眼内压力动态
背景情况:
- 主角闭合 (PAC) 和主角闭合玻璃眼 (PACG) 可以呈现正常的眼内压力 (IOP).
- 二十四小时内血压波动是诊断和管理角关闭疾病的关键,但尚未研究的参数.
- 外周前侧 (PAS) 是角关闭疾病的标志,可能会影响IOP动态.
研究的目的:
- 为了研究慢性初级角关闭疾病中的24小时内压模式.
- 评估这些患者的PAS程度与24小时内血压模式之间的关联.
主要方法:
- 一项前性队列研究,涉及35名亚洲患者的59只眼睛,患有慢性原发性角关闭性疾病.
- 在2小时间隔使用戈德曼平面化度仪进行24小时内脉的监测.
- 在疾病的不同阶段比较峰值,平均值,低谷内血压和24小时内血压波动.
主要成果:
- 与PACS眼睛相比,用PAC和PACG眼睛的峰值IOP和24小时IOP波动显著更高.
- PACG眼睛显示24小时内血压波动最高.
- 帕斯的程度与PAC和PACG眼中的峰值,平均值和24小时IOP波动有显著的关联.
结论:
- 与PACS相比,PACG和PAC中的24小时IOP波动显著增加.
- 尽管高峰IOP和波动,谷IOP在大多数PAC和PACG眼中仍然低于21 mmHg.
- 帕斯的程度是影响24小时内血压模式的关键因素,主要是关闭角度疾病.
相关概念视频
Angle Closure Glaucoma: Treatment
560
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
560
Glaucoma: Overview
621
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
621
Open Angle Glaucoma: Treatment
479
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
479


