在早期复发缓解多发性硬化症中改变了社会认知
Renato Oliveira1, Gonçalo Diniz de Pinho2, Dina Silva2
1Department of Neurology, Hospital da Luz Lisboa, Lisbon, Portugal; Neuroimmunology clinic, Hospital da Luz Lisboa, Lisbon Portugal; Comprehensive Health Research Centre, Universidade Nova de Lisboa, Lisbon, Portugal.
Multiple sclerosis and related disorders
|August 11, 2023
概括
社会认知缺陷,包括心理理论 (ToM),在早期多发性硬化症 (MS) 中存在. 影响性TOM似乎独立于MS患者的其他认知障碍.
科学领域:
- 神经科学是一个神经科学.
- 临床心理学 临床心理学
- 神经学 神经学
背景情况:
- 社会认知 (SC) 对于社会互动至关重要,但在早期多发性硬化症 (MS) 中没有得到很好的定义.
- 目前尚不清楚MS中SC缺陷是否独立于一般认知障碍.
研究的目的:
- 为了比较早期复发性复发性多发性硬化症 (RRMS) 患者的社会认知 (SC) 测量与匹配的对照组.
- 调查SC,认知功能和早期MS的临床因素之间的关系.
主要方法:
- 一项横截面研究,将38名早期RRMS患者与38名健康对照人进行比较.
- 通过情绪识别任务,眼睛阅读思维测试 (RMET) 和虚假传递测试 (FPT) 评估SC.
- 评估了一般认知,抑郁,焦虑,疲劳和生活质量.
主要成果:
- 34.2%的早期RRMS患者表现出改变的社会认知 (SC).
- 与对照组相比,MS患者在认知和情感思维理论 (ToM) 中表现较差;在面部情感识别 (FER) 中没有差异.
- 认知ToM和FER与认知功能相关,但情感ToM没有;生活质量差与改变的SC有关.
结论:
- 社会认知障碍,特别是ToM缺陷,在早期RRMS中很普遍.
- 认知性ToM和FER与一般认知状态相关,而情感性ToM在早期MS中似乎独立于其他认知功能.
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