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在重大创伤后的体外膜氧化支持患者中,死亡率的预测因素

Joep J J Ouwerkerk¹, Ander Dorken-Gallastegi², Benjamin C Renne²

¹Division of Trauma, Emergency Surgery, and Surgical Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Division of Trauma Surgery, Leiden University Medical Center, Leiden, Netherlands.

The Journal of surgical research

|August 11, 2023

概括

在创伤患者的体外膜氧化 (ECMO) 正在增加. 女性性别,低格拉斯哥昏迷度量表,年龄较大和严重的外伤独立预测这些患者的死亡率.

科学领域:

创伤外科手术创伤外科
关键护理医学关键护理医学
医疗信息学医疗信息学

背景情况:

在创伤患者中,体外膜氧化 (ECMO) 的使用增加了.
有限的数据存在于预测该人口的发病率和死亡率的因素.
确定死亡率预测因素对于指导未来研究至关重要.

研究的目的:

为了确定患者特征独立与ECMO治疗中创伤患者的死亡率相关.
提供数据以指导未来的研究和临床决策.

主要方法:

对创伤质量改善计划数据库 (2010-2019) 的回顾性分析.
包括接受ECMO的成年创伤患者 (≥16岁).
多变量回归建模以确定死亡率的独立预测因素.

主要成果:

女性性别,表现后4小时内ECMO,格拉斯哥昏迷尺度下降,年龄增加以及4小时内输血的单位与死亡率有关.
外部伤害 (≥3) 是最强的预测因素,死亡风险增加了29.5%.

结论:

多种因素独立地与ECMO创伤患者的死亡率有关.
需要对影响结果的非伤害特征 (例如,Pao2/Fio2比,ARDS分类) 进行进一步的研究.

关键词:

身体外膜氧化器的氧化死亡率死亡率死亡率创伤是一个创伤.

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