在带有或没有术前预防性抗生素覆盖的开放性脊髓切除术后,对手术部位感染的回顾性评估
Benjamin Andrea Husi1, Laura Arnaldi1, Moritz Roitner1
1Clinic for Small Animal Surgery, Vetsuisse Faculty, University of Zurich, Switzerland.
Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
|August 11, 2023
概括
术后预防性抗生素 (PPA) 不是必要的狗经历了切除术,即使在较高的ASA分数. 这项研究发现手术部位感染率较低,这表明PPA可能不需要用于此程序.
科学领域:
- 兽医外科 兽医外科 兽医外科
- 预防传染病 预防传染病
- 抗微生物药物管理委员会
背景情况:
- 周术预防性抗生素 (PPA) 是兽医学中预防手术部位感染 (SSI) 的标准.
- 目前的指导方针缺乏PPA使用的具体程序建议,特别是在犬脊髓切除术中.
- 一般指导方针建议PPA用于手术>90分钟或在患有美国麻醉学会 (ASA) 类≥3.3的患者.
研究的目的:
- 评估PPA在狗开放性脊髓切除术后预防SSI的疗效.
- 为了确定脊髓切除术,特别是在高风险患者中,是否有必要进行例行PPA.
- 通过评估PPA对于这种特定的外科手术程序的必要性,为抗菌药物管理提供信息.
主要方法:
- 对112只经过脊髓切除术的狗进行了回顾性审查 (10/2017-01/2023).
- 收集的数据包括患者人口统计,手术细节,麻醉参数和PPA的使用情况.
- 需要进行手术后30天的随访,以包括.
主要成果:
- 46只狗接受了PPA,66只没有;大多数狗是ASA类3或更高.
- 在非PPA组中,只有一个SSI发生 (1.5%SSI率),导致整体SSI率为0.9%.
- 由于SSI的发病率很低,因此无法对风险因素进行统计分析.
结论:
- 狗的切除术,即使是ASA等级3或更高的狗,似乎也有SSI的低风险.
- 这些发现表明,PPA可能不会在狗脊髓切除术中常规使用.
- 减少在脊髓切除术中使用PPA可能会显著降低兽医实践中的整体抗菌药物负担.
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