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在CD45-ADC之后的移植可以在先天性和单独的环境中纠正Rag1免疫缺陷

Francesca Pala1, Cristina Corsino1, Enrica Calzoni1

  • 1Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.

The Journal of allergy and clinical immunology
|August 11, 2023
PubMed
概括

使用CD45-抗体药物合物 (CD45-ADC) 的新调节方法使得在免疫缺陷与免疫失调 (CID-ID) 联合免疫缺陷模型中,即使是与单一的捐赠者,也能够成功地移植造血细胞.

关键词:
在CD45-ADC中使用CD45-ADC.在RAG RAG的基础上.条件调节方案的调节方案.植入方式 植入方式 engraftment造血细胞移植 造血细胞移植免疫调节失调 免疫调节失调免疫复合 免疫复合 免疫复合免疫缺陷是一种免疫缺陷.

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