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长非编码RNA LOC100909675和转录调节器CTCF的合作调节Cdk1转录以控制天体细胞增殖

Ronghua Wu1, Haixu Lin1, Wei Zhang1

  • 1Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products, Nantong University, Nantong, China.

The Journal of biological chemistry
|August 11, 2023
PubMed
概括

长非编码RNA LOC100909675 (LOC9675) 在脊髓损伤后促进星球细胞的增殖. 它与CTCF的相互作用调节了循环素依赖性激酶1 (Cdk1) 的mRNA稳定性,为神经再生疗法提供了一个新的点.

关键词:
CTCF (CCCTC-约束因素) 是一个关键因素.Cdk1 (循环林依赖激酶1) 是一种星球细胞是星球细胞.在 lncRNA LOC10090967575 中.脊髓损伤导致的脊髓损伤

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