瓶装,中性pH电解氧化水的与储存相关的稳定性和抗菌疗效
C S Krishnan1, K M Lyons1, G R Tompkins1
1Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin, New Zealand.
Journal of dentistry
|August 11, 2023
概括
准备使用的中性pH电解氧化水 (EOW) 在适当储存时保持稳定五个月. 这种稳定的EOW是一种有效的假牙消毒剂,可以对抗像Candida albicans这样的有害微生物.
科学领域:
- 微生物学 微生物学
- 生物技术是生物技术.
- 老年学是指老年学的学科.
背景情况:
- 假牙口腔炎是老年人常见的口腔感染,对健康造成重大风险.
- 准备使用 (RTU) 中性pH电解氧化水 (EOW) 是一种公认的环境消毒剂,用于医疗机构.
- 需要对RTU EOW在假牙消毒中的稳定性和有效性进行研究.
研究的目的:
- 为了评估RTU中性-pH EOW的储存稳定性.
- 评估RTU EOW对相关口腔病原体的抗菌活性.
- 为了确定RTU EOW对Candida albicans在假牙树脂上的生物膜的疗效.
主要方法:
- 在各种温度下 (4°C,室温,37°C) 储存RTU EOW溶液长达28天,并对化学性质进行监测.
- 用不同的接触时间对黄金葡萄球菌和白虫菌细胞进行了抗菌活性测试.
- 进行了最小抑制度 (MIC90) 和生物膜减少试验.
主要成果:
- 当RTU EOW在4°C或室温下存储长达五个月时,保持稳定的低酸 ([HOCl]) 水平.
- 与EOW接触的短时间 (1分钟) 实现了细菌和真菌细胞计数的显著log10减少.
- EOW有效地将Candida albicans生物膜的代谢活性降低了86%.
结论:
- 在长时间的储存期间,RTU中性-pH EOW 显示出出色的稳定性.
- EOW是一种强大的抗菌剂,有效对浮游生物细胞和与假牙口腔炎相关的生物膜产生作用.
- RTU EOW是一种可行的,有效的假牙消毒剂,有潜力预防老年人口腔角膜炎.
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