更高的心血管巴罗反射灵敏度预测心胸外科手术后增加疼痛结果
Heberto Suarez-Roca1, Negmeldeen Mamoun2, Lana L Watkins3
1Center for Translational Pain Medicine, Duke University Medical Center, Durham, North Carolina.
手术前心血管巴罗反射敏感度 (BRS) 预测心胸手术后的术后疼痛. 较高的BRS与疼痛增加有关,这表明了疼痛管理的新工具.
科学领域:
- 心血管生理学心血管生理学
- 疼痛管理 疼痛管理
- 外科手术的结果
背景情况:
- 术后疼痛显著影响康复,增加住院时间和费用.
- 严重的术后疼痛的预测因素仍然不完全理解.
- 巴罗受体功能,影响疼痛处理和炎症,是一个潜在的因素.
研究的目的:
- 调查心血管巴罗反射灵敏度 (BRS) 是否可以预测术后疼痛.
- 评估心胸外科手术患者手术前BRS和疼痛结果之间的关系.
- 探索炎症在BRS疼痛关联中的作用.
主要方法:
- 在手术前对55名患者进行自发心血管BRS评估.
- 使用疼痛,快乐和一般活动等级和压力疼痛值测量术后疼痛.
- 在手术前和后监测炎症生物标志物 (CRP,白蛋白,细胞因子).
主要成果:
- 手术前的BRS显著预测了手术后的疼痛 (P=.013).
- 较高的BRS与术后第二天的疼痛增加有关,独立于其他因素.
- BRS与影响一般活动和享受的疼痛相关,但不影响疼痛强度或压力值.
结论:
- 手术前心血管BRS是术后疼痛的独立预测因子.
- BRS可以作为一个可修改的目标来优化疼痛管理策略.
- 巴罗受体功能在术后疼痛中发挥着作用,超出了炎症和疼痛敏感性.
更多相关视频
07:14A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
Published on: January 18, 2018
04:48Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery
Published on: November 28, 2018
相关概念视频
Neural Regulation of Blood Pressure
Baroreceptor Reflex
Baroreceptors, located in the carotid sinuses and aortic arch, detect changes in blood pressure. When blood pressure rises, these stretch-sensitive receptors...
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Disorders of the Autonomic Nervous System
Raynaud's disease, also known as Raynaud's...
Regulation of the Cardiovascular System
The regulation of the cardiovascular system involves the autonomic nervous system (ANS), baroreceptors, and chemoreceptors, ensuring that heart rate and blood pressure are appropriately modulated in response to varying physiological demands.
The ANS comprises two main divisions: the sympathetic and parasympathetic nervous systems. The sympathetic nervous system enhances...
Peripheral Artery Disease V: Postoperative Nursing Management
Heart Failure II: Pathophysiology
