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在整个月经周期内,通过连续血糖监测器测量血糖变异
Georgianna Lin1, Rumsha Siddiqui2, Zixiong Lin3
1University of Toronto, Computer Science, Toronto, ON, Canada. blue.lin@mail.utoronto.ca.
NPJ digital medicine
|August 11, 2023
概括
在整个月经周期中,血糖水平呈现出双相模式,在黄质期达到峰值,并在卵泡后期达到最低. 这些葡萄糖波动与激素水平和生活方式因素相关.
科学领域:
- 内分泌学 在内分泌学.
- 代谢健康 代谢健康
- 生殖健康 生殖健康
背景情况:
- 之前关于月经周期血糖变化的研究,由于采样不频繁,导致不一致的结果.
- 了解整个月经周期的葡萄糖动态对于妇女健康至关重要.
研究的目的:
- 通过使用持续监测,研究血糖水平与月经周期之间的关系.
- 为了确定与显著的葡萄糖波动相关的特定月经周期阶段.
- 探索葡萄糖水平,荷尔蒙变化和自我报告的症状之间的相关性.
主要方法:
- 利用49名参与者的连续血糖监测 (Dexcom G6) 和智能手表数据 (Fitbit Sense) 在149个月经周期中.
- 采用定期限制立方线和混合效应模型来分析基于阶段的葡萄糖变化.
- 收集月经激素的日常数据和自我报告的症状,如食欲,疲劳和胀气.
主要成果:
- 每日平均葡萄糖水平表现出双相模式,在黄质期达到峰值,在状期达到最低.
- 这些葡萄糖趋势在调整参与者特征 (年龄,BMI,体重) 和自我报告的症状后保持一致.
- 更高的葡萄糖水平与更低的雌激素,更少的步骤和轻微的疲劳有关,而增加的食物渴望与更高的葡萄糖相关.
结论:
- 血糖水平在整个月经周期中表现出可预测的波动.
- 雌激素水平,体力活动和食欲与与月经周期相关的葡萄糖变化有关.
- 血糖监测可以提供有关月经健康的见解,这需要进一步研究周期特定的葡萄糖动态.
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