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使用二维斑点跟踪回声心脏学在败血症患者心肌层特异性菌株的定量评估

Jin Zhang¹, Jing Zhu², Tian Xie¹

¹Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.

BMC anesthesiology

|August 11, 2023

概括

败血症患者的层特异性菌株揭示了心肌功能障碍,即使在没有减少喷射率的患者中也是如此. 这一发现突出显示了败血症中微妙的心脏变化,影响心表层.

科学领域:

心脏病学心脏病学
关键护理医学关键护理医学
心声回声扫描 (Echocardiography) 是一种心声回声扫描.

背景情况:

全球纵向应变 (GLS) 在败血症中减少,并与不良结果相关.
在败血症中,层特异的左心室 (LV) 菌株尚不清楚.
在败血症患者中评估心肌功能障碍需要详细的应变分析.

研究的目的:

在败血症患者中研究层特异的左心室 (LV) 菌株.
评估层特异性菌株在毒期间识别心肌功能障碍时的实用性.
为了比较败血症诱导心肌病 (SICM) 和非SICM组之间的应变模式.

主要方法:

在第三级医院进行前性观察性研究.
在入学后24小时内进行的二维斑点跟踪回声心脏图.
对人口统计数据,实验室值,临床结果和特定层LV菌株的分析.

主要成果:

包括79名败血症患者;22名在SICM (LVEF < 50%) 和57名在非SICM (LVEF ≥ 50%) 中.
与非SICM患者相比,SICM患者表现出较少的负面层特异性和全球菌株.
没有SICM的患者表现出明显更糟糕的心表纵向应变 (LS-epi) 比健康对照 (-18.5%对 -21.4%,p=0.024).

结论:

大多数败血症患者 (72.2%) 呈现了保存的喷射分数 (非SICM).
微妙的心肌损伤,以降低的LS-epi表示,即使在没有明显的缩功能障碍的败血症患者中也存在.
层特异性菌株分析,特别是LS-epi,对于在败血症中检测早期心肌功能障碍至关重要.

关键词:

在 GLS 中使用.一层特定的菌株.左心室,败血症引起的心肌病.败血症这是一种败血症.

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