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在光滑肌肉中CFTR功能障碍驱动TGFβ依赖的气道过敏反应

Elizabeth L Kramer1,2, Kristin M Hudock3,4, Cynthia R Davidson5

  • 1Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA. elizabeth.kramer@cchmc.org.

Respiratory research
|August 11, 2023
PubMed
概括

囊性纤维化 (CF) 呼吸道阻塞涉及光滑肌肉功能障碍. 转化生长因子β1 (TGFβ) 在CF中直接影响气道光滑肌 (ASM),导致气道过敏反应 (AHR).

关键词:
气道的过度反应性呼吸道光滑肌肉的肌肉.在CFTR中,CFTR是最重要的.囊性纤维化症是什么转化增长因子β的转化增长因子β.

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