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早期正常和高血压伪皮性玻璃眼之间的OCT和OCTA检查模式的差异

Urszula Łukasik¹, Dominika Wróbel-Dudzińska¹, Jaromir Jarecki²

¹Department of Diagnostics and Microsurgery of Glaucoma, Medical University of Lublin, Chmielna Str. 1, 20-079 Lublin, Poland.

Journal of clinical medicine

|August 12, 2023

概括

早期的正常张力玻璃眼 (NTG) 与高压伪除性玻璃眼 (HTG) 相比,显示出较薄的时间视网膜神经纤维层 (RNFL). 光学连贯断层扫描血管学 (OCTA) 显示,早期NTG和HTG之间没有血管差异.

科学领域:

眼科医生眼科眼科
玻璃眼研究研究玻璃眼研究
医疗成像医学成像

背景情况:

玻璃眼是导致不可逆转失明的主要原因.
正常张力玻璃眼 (NTG) 和高压伪皮玻璃眼 (HTG) 是不同的亚型.
早期诊断和区分对于有效管理至关重要.

研究的目的:

为了比较光学连贯性断层扫描血管学 (OCTA) 和光学连贯性断层扫描 (OCT) 早期NTG与HTG的发现.
调查潜在的血管对NTG病变的贡献.
为了确定这些绿眼类型之间的视神经头部和斑块的结构差异.

主要方法:

对70只出现早期NTG的眼睛和71只出现早期HTG的眼睛进行比较研究.
标准眼科检查,包括光盘评估.
视光盘OCT与周状视网膜神经纤维层 (RNFL) 厚度测量.
使用Zeiss Cirrus 5000进行斑点和光盘的OCTA.

主要成果:

无论是NTG和HTG组,均呈现出相似的平均偏差 (MD) 和早期绿内障.
在部部门发现了周周毛囊RNFL厚度的统计学上显著差异,在NTG组RNFL较薄 (53.94比59.94,p=0.0071).
通过OCTA,在早期的NTG和HTG组之间没有观察到斑点或光盘血管密度和流量参数的显著差异.

结论:

血管因素似乎没有在早期正常张力玻璃眼病的发病过程中发挥主导作用.
这些发现支持时间RNFL在早期NTG中的更大参与.
在早期NTG和HTG之间,OCTA没有发现血管参数的差异,这表明有不同的潜在机制.

关键词:

有关OCT的血管学.早期的玻璃眼 glaucoma 的情况.玻璃眼 glaucoma 玻璃眼玻璃眼玻璃眼玻璃眼高压玻璃眼的高压玻璃眼.正常血压的玻璃眼 (glaucoma) 是一种正常血压的玻璃眼.伪皮性玻璃眼 (Glaucoma) 是一种

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