父亲年龄很重要:与精子标准的关联 - - 精子体的DNA完整性和甲基化概况

Marwa Lahimer1,2,3, Debbie Montjean4, Rosalie Cabry1,2

  • 1Reproductive Medicine, Reproductive Biology & Genetics, University Hospital and School of Medicine, Picardie University Jules Verne, CHU Sud, 80054 Amiens, France.

PubMed
概括

40岁以上的高级父亲年龄 (APA) 增加了精子DNA碎片化,降低了DNA甲基化. 生育能力评估应考虑对老年男性进行DNA碎片化测试.

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