在西班牙北部一家三级医院接受肝移植的接受者的个人资料
Janet Pagnozzi1, Yuri Álvarez2, Ignacio González-Pinto3
1Área de Gestión Clínica de Geriatría, Hospital Monte Naranco, Avenida Doctores Fernández Vega 107, 33012 Oviedo, Spain.
Journal of clinical medicine
|August 12, 2023
概括
这项研究分析了西班牙阿斯图里亚斯的肝移植 (LT) 接受者,发现典型的患者是中年男性,患有晚期酒精性肝病. 生存率与国家数据相比较,突出显示需要进行区域移植特征分析.
科学领域:
- 肝病学和移植外科手术
- 胃肠病学 胃肠病学
- 公共卫生和流行病学
背景情况:
- 西班牙在人均肝移植 (LT) 率方面世界领先.
- 阿斯图里亚斯州的接受者和捐赠者的个人资料不同于全国平均水平.
- 了解区域LT接收者的特点对于优化护理至关重要.
研究的目的:
- 对阿斯图里亚斯的肝移植 (LT) 接受者进行初步分析.
- 为了检查LT手术和术后期的特征.
- 将阿斯图里亚斯的LT结果与现有文献进行比较.
主要方法:
- 在2002年至2017年期间对533个LTs进行了回顾性,描述性,横截面研究.
- 对接受者人口统计,肝病病因和手术/术后数据的分析.
- 多变量考克斯回归模型用于确定总生存期的预后因素.
主要成果:
- 典型的接受者是男性 (平均年龄为55.1岁),患有晚期酒精性肝病 (儿童C期).
- 常见的并发症包括初级移植功能障碍和肝动脉血栓;II级克拉维恩-丁多最常见.
- 平均存活时间为13年,5年和10年存活概率分别为79.3%和61.9%.
结论:
- 阿斯图里亚斯的LT接受者主要是超重的男性,患有晚期酒精性或病毒性肝病.
- 术后并发症和生存率与国家和国际基准可比.
- 建议对外科特殊情况和长期随访进行进一步的研究,以获得全面的区域视图.
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