卵巢囊反应在辅助生殖技术中被Salpingectomy改变:一个术前和术后的病例控制研究
Laurianne Reitz1,2,3, Vincent Balaya3, Basile Pache4,5
1Obstetrics and Gynecology Department, Foch Hospital, 92150 Suresnes, France.
Journal of clinical medicine
|August 12, 2023
概括
单侧切除术是一种切除一个输卵管的手术,可能会减少辅助生殖技术 (ART) 周期可用的成熟卵巢卵泡的数量. 这一发现凸显了在妇科手术中保护生育能力的重要性.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 妇科外科手术 妇科外科
- 辅助生殖技术 (ART) 是一种辅助生殖技术.
背景情况:
- 单侧切除术是一种常见的妇科手术.
- 它对随后的辅助生殖技术 (ART) 周期中的卵巢卵泡招募的影响尚未完全理解.
- 评估这种影响对于优化生育结果至关重要.
研究的目的:
- 为了评估单侧salpingectomy在ART期间对双侧卵巢成熟卵泡数量的影响.
- 为了比较经过手术的卵巢中的卵泡数量与手术后的对侧卵巢的卵泡数量.
- 为了告知外科指示和生育保存策略.
主要方法:
- 回顾性,单中心,病例控制队列研究 (2017-2022年).
- 包括24名患者 (18-43岁) 在单侧切除术前后接受ART治疗.
- 在两个ART周期中,比较了ipsilateral (salpingectomy) 和contralateral卵巢中的成熟卵泡 (≥16毫米).
主要成果:
- 在手术前,卵巢之间成熟的卵泡没有显著差异.
- 在手术后的卵巢salpingectomy (3.00对5.08,p=0.048) 中,平均成熟卵泡显著减少.
- 在中间或总招募的毛囊中没有显著的差异.
结论:
- 切除术可能会对双侧卵巢卵泡的招募产生负面影响,可能是由于血管化的改变.
- 妇科医生在设定手术指示时应考虑这种影响.
- 强调需要在ART患者的生育能力保护方面熟练的外科医生.
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