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心肌梗塞后心血管患者的认知障碍:前性临床研究
Dominika Kasprzak1, Katarzyna Kaczmarek-Majer2,3, Janusz Rzeźniczak1
1Department of Cardiology, J. Strus Hospital, 61-285 Poznań, Poland.
Journal of clinical medicine
|August 12, 2023
概括
认知障碍 (CI) 影响了心肌梗塞 (MI) 后37%的患者,在六个月后降至25%. 心脏功能和动脉样硬化的严重程度会影响这些患者的CI发展.
科学领域:
- 心脏病学 心脏病学
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
背景情况:
- 对心脏病患者来说,认知功能评估不是标准的,这限制了当前的知识.
- 心肌梗塞 (MI) 可能会影响认知健康,需要进一步调查.
- 了解心脏病后的认知功能对于全面的患者护理至关重要.
研究的目的:
- 评估心肌梗塞 (MI) 后患者认知障碍 (CI) 的频率.
- 确定影响CI后MI发生和持续的因素.
- 评估心脏病发作后六个月内认知功能的变化.
主要方法:
- 一项前性研究,涉及468名因心脏病入院的患者.
- 认知功能被评估了两次:在初次住院期间和在MI后的六个月.
- 迷你精神状态检查 (MMSE) 被用来检测认知障碍.
主要成果:
- 在住院期间,认知功能障碍存在于37%的患者中,在六个月后降至25% (p < 0.001).
- 诸如GFR,BNP,射出分数和SYNTAX等因素分辨出最初患有CI的患者;在六个月后,LDL和HCT水平显著.
- 观察到非认知性精神障碍的高患病率,包括抑郁症和睡眠障碍.
结论:
- 后心脏病患者表现出认知障碍和其他心理健康问题的高患病率.
- 心脏功能恶化 (EF,BNP),冠状动脉样硬化严重程度 (SYNTAX),红细胞参数和LDL水平显著影响后心脏病患者的CI.
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