在诱导阶段B型急性淋巴细胞白血病的成年人进行交叉训练和抵抗训练:随机盲人试点研究
Adán Germán Gallardo-Rodríguez1,2, Vanessa Fuchs-Tarlovsky3, María Esther Ocharán-Hernández4
1Research in Medicine Program, Instituto Politécnico Nacional, Mexico City 11340, Mexico.
Journal of clinical medicine
|August 12, 2023
概括
运动干预措施,包括交叉训练和抵抗训练,可以在化疗期间改善急性淋巴细胞白血病 (ALL) 患者的身体组成和身体表现. 这些发现表明,综合性运动可能作为辅助治疗有益.
科学领域:
- 在瘤学瘤学.
- 运动生理学 运动生理学
- 康复 康复 康复 康复
背景情况:
- 接受诱导化疗的急性淋巴细胞白血病 (ALL) 患者体验了身体能力,肌肉质量和生活质量 (QOL) 的下降.
- 虽然化疗期间的运动是安全和有益的,但交叉训练的具体效果仍未得到研究.
研究的目的:
- 评估交叉训练运动对ALL患者体质组成,身体表现和QOL的影响.
- 为了比较交叉训练运动组 (CEG) 和抵抗运动组 (REG) 与对照组 (CG) 的影响.
主要方法:
- 一个盲目的随机临床试验,涉及33名ALL患者.
- 患者被分配到CEG,REG或CG,在诱导期间接受监督的炼3-5天/周30-50分钟.
- 在基线,出院和2个月的随访期间,测量了身体组成,身体表现和QOL.
主要成果:
- 无论是REG和CEG都显示了身体组成的改善,而CG则经历了肌肉质量的减少和脂肪质量的增加 (p=0.020).
- 与CG相比,在REG和CEG中观察到体力表现的显著改善.
- 在两组之间没有发现QOL的显著差异 (p=0.340).
结论:
- 交叉训练和抵抗运动对于在ALL诱导疗法期间增强身体组成和身体表现至关重要.
- 鉴于体力表现的预后重要性,综合性炼计划被建议作为成人ALL患者的辅助治疗.
相关概念视频
Bone Marrow Sampling and Transplants
360
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
360
Cells of the Adaptive Immune Response
1.0K
The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
1.0K
Stem Cell Therapy for Tissue Regeneration
4.1K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.1K


