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Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
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在术后晚期的Roux-En-Y胃绕道中,相位角度,炎症和萨科佩尼亚
Gisele Florêncio1, Aglécio Souza1, Elinton Chaim2
1Department of Internal Medicine, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas 13083-887, Brazil.
Journal of clinical medicine
|August 12, 2023
概括
这项研究发现,生物电阻分析 (BIA) 的相角 (PhA) 和身体组成指标与胃绕道手术前后年轻成年人的肉相关,表明早期肌肉功能下降.
科学领域:
- 腹部外科 腹部外科
- 身体组成分析 身体成分分析
- 老年医学 (尽管研究重点是年轻人)
背景情况:
- 肥胖症 (sarcopenic obesity) 是一种肌肉质量与多余脂肪的损失,通常在老年人中进行研究.
- 鲁克斯-en-Y胃绕道手术 (RYGB) 可以导致显著的身体组成变化.
- 早期发现RYGB后的肉症对于长期健康结果至关重要.
研究的目的:
- 研究RYGB之前和之后的年轻成年人中相角 (PhA) 和麻症之间的关系.
- 评估生物电阻分析 (BIA) 在识别肉症标志物的有用性.
主要方法:
- 评估了69名成年人 (46名女性,23名男性;平均年龄38.5岁) 接受RYGB的队列.
- 使用BIA测量身体成分和PhA.
- 萨科佩尼亚通过DXA通过手握强度 (HGS),步行速度 (GS) 和尾瘦质量 (ALM) 进行评估.
主要成果:
- 手术后的患者在BIA上显示出明显较低的PhA和较高的抗性 (R) (分别p < 0.0007和p = 0.0026).
- HGS和GS与BIA抵抗有负相关性 (R).
- ALM与BIA反应性和抗性 (R) 有负相关性.
结论:
- PhA和BIA成分与肉症标志物有效相关,特别是肌肉功能下降.
- 在经过胃绕道术的个体中,BIA可以识别肌肉功能下降的早期迹象.
- 这些发现强调了监测腹部外科手术患者的肌肉健康的重要性.
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