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全球流行病学和老年人发病的炎症性肠病的负担:十年的回顾
Pojsakorn Danpanichkul1, Kanokphong Suparan1, Suchapa Arayakarnkul2
1Immunology Unit, Department of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Journal of clinical medicine
|August 12, 2023
概括
老年发病的炎症性肠病 (IBD) 正在增加,特别是在男性中,现在占所有病例的13%. 虽然死亡率正在下降,但发达国家的死亡负担仍然很高.
科学领域:
- 胃肠病学 胃肠病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 炎症性肠病 (IBD) 传统上影响年轻人群.
- 老年人发病的IBD (65岁以上) 具有独特的挑战,包括增加的并发症和诊断困难.
- 全球关于老年人发病IBD的流行病学数据有限.
研究的目的:
- 分析十年来老年发病IBD的全球趋势.
- 估计老年发病IBD的年度频率和年龄标准化率.
- 根据性别,地理和社会人口因素对IBD负担进行分层.
主要方法:
- 对十年来全球IBD流行病学数据的分析.
- 估计年频率和年龄标准化发病率.
- 按性别,地理区域和社会人口统计指数 (SDI) 划分数据的分层.
主要成果:
- 老年人发病的IBD约占所有IBD病例的13%.
- 男性的发病率正在上升,但女性的发病率正在下降.
- 西太平洋的发病率升最高;美国和高SDI国家的负担最高.
- 死亡率和残疾调整寿命年 (DALYs) 率在全球范围内正在下降.
结论:
- 老年发病IBD的发病率和比例显著增加,特别是在男性中.
- 尽管死亡率和DALYs下降,但高收入地区的整体负担很大.
- 公共卫生战略和进一步的研究对于解决日益增长的老年IBD负担至关重要.
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