帕金森病患者的关节评估:一项比较研究
Ayse Selenge Akbulut1, Aysun Hatice Akca Karpuzoglu2
1Department of Orthodontics, Peri Sokak Dental Clinic, 42010 Konya, Türkiye.
Diagnostics (Basel, Switzerland)
|August 12, 2023
概括
关节 (TMJ) 形态在帕金森病 (PD) 患者和健康个体之间有显著差异. 这项研究强调TMJ不对称性是与帕金森病相关的潜在指标.
科学领域:
- 医疗成像医学成像
- 神经学 神经学
- 矯正牙科 矯正牙科是一種矯正牙科.
背景情况:
- 帕金森病 (PD) 是一种影响运动功能的神经退行性疾病.
- 关节 (TMJ) 疾病会影响生活质量和功能.
- 了解PD患者的TMJ形态对于全面的患者护理至关重要.
研究的目的:
- 为了评估患有帕金森病 (PD) 的患者中关节 (TMJ) 形态.
- 识别和比较在PD患者和健康对照者之间TMJ的形态差异.
主要方法:
- 磁共振成像 (MRI) 用于评估102名高加索人 (51名PD患者,51名健康对照) 的10个TMJ参数.
- 进行了统计分析,包括对的样本t-test和学生的t-test,显著程度为p < 0.05.
- 计算了不对称性指数,以比较两个组之间的TMJ参数.
主要成果:
- 所有测量的关节参数都显示了PD组的统计学上显著的交叉差异 (p < 0.05).
- 健康对照组仅在状骨 (LAC) 长轴 (p < 0.05) 中表现出显著差异,其他参数没有显著的横向差异 (p > 0.05).
- 对于大多数TMJ参数的不对称指数在PD组与对照组相比显著更高 (p <0.05).
结论:
- 在帕金森病患者中存在显著的TMJ不对称性.
- 这些发现表明TMJ形态,不对称性和帕金森病之间存在潜在的关联.
- 需要进一步的研究来探索这些TMJ变化的PD的临床影响.
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