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关于COVID-19的长期影响的常规脑部MRI发现:一个范围审查

Yuriy Vasilev¹, Ivan Blokhin¹, Anna Khoruzhaya¹

¹Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies, Department of Health Care of Moscow, Russian Federation, Petrovka Street, 24, Building 1, 127051 Moscow, Russia.

Diagnostics (Basel, Switzerland)

|August 12, 2023

概括

常规的大脑MRI扫描显示在诊断后COVID状态 (PCC) 中的价值有限. 常见的发现,如周血管空间和微型血液,并不特定于PCC,表明缺乏明显的MRI生物标志物.

科学领域:

神经成像是一种神经成像.
神经学神经学
传染性疾病传染性疾病

背景情况:

后COVID状态 (PCC) 经常表现为持续的神经精神疾病症状.
磁共振成像 (MRI) 提供了关于PCC中的大脑代谢,连接和结构的见解.
先进的MRI技术在常规的临床实践中并不容易获得.

研究的目的:

在COVID后病情患者中对常规脑部MRI发现进行范围审查.
在临床实践中识别与PCC相关的已确定的MRI异常.

主要方法:

在PubMed数据库中进行了全面的文献搜索,截至2023年4月.
包括的研究是以英语出版的队列,截面和前后设计.
先进的MRI序列,预印件和病例报告被排除在外,以专注于例行发现.

主要成果:

七项涉及451名患者的研究被纳入了审查.
最常见的MRI发现是周血管空间 (47%),微型血液 (27%),以及白质病变 (10%).
关于与PCC相关的特定MRI异常存在显著缺乏共识.

结论:

磁力共振成像结果的异质性和对异常的低一致性限制了它们在PCC中的诊断实用性.
常规的大脑MRI协议目前为诊断长期COVID提供了最小的价值.

关键词:

诊断测试诊断测试测试诊断测试影像成像技术影像成像技术长时间的COVID.磁共振是一种磁共振.一个常规的日常生活.范围审查范围审查范围审查

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