在体外消化过程中,被封装在素菌根中的人类素的释放行为
Uzma Sadiq1, Fatima Shahid2, Harsharn Gill1
1School of Science, RMIT University, Bundoora, Melbourne, VIC 3083, Australia.
Foods (Basel, Switzerland)
|August 12, 2023
概括
在菌素微粒 (CMs) 中封装甲类素,可以防止降解. 不同形式的封装式 antraquinones 显示在消化过程中各种释放,粉末形式提供更好的保留和控制释放.
科学领域:
- 食品科学 食品科学 食品科学
- 营养保健品 营养保健品
- 生物材料是一种生物材料.
背景情况:
- 来自花的 antraquinones 具有生物活性性质,但容易降解.
- kazein micelles (CMs) 是一种食品级材料,用于封装和保护生物活性化合物.
研究的目的:
- 为了研究在体外消化过程中,在菌素中封装的草中获得的 antraquinones 的消化行为.
- 为了比较口腔,胃和肠道消化过程中不同形式的封装素 (粉末和整个凝) 的释放特征.
主要方法:
- 喷雾干燥和冷干燥技术被用于制备装有叶真 antraquinones 的casein micelle微囊.
- 采用了模拟口腔,胃和肠道条件的体外消化模型.
- 分析的重点是微囊的结构完整性和 antraquinones 的释放动力学.
主要成果:
- 装有 antraquinone 粉末 (CMAQP 和 CMFDP) 的 casein micelle 微囊在胃消化过程中表现出缓慢的溶解和奶酪形成,增强了保留.
- 全叶凝 (CMWLAG) 微囊在早期消化阶段表现出结构分解和过早释放的 antraquinone.
- 虽然这两种粉末形式都在模拟肠液 (SIF) 中释放 antraquinones,但CMAQP 随着时间的推移显示出更受控的释放特征.
结论:
- 素微粒有效地保护花,粉末形式提供优越的保护和控制释放,与整个凝相比.
- 生物活性成分的物理形式显著影响其在体外消化过程中的释放行为.
- 这项研究强调了食品级 kazein micelles 开发稳定有效的营养药品的潜力.
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