隔离的奥克-糖化基托-乳清蛋白对乳液特性,阿斯塔山丁溶解性,稳定性和生物可访问性的影响
Lingyu Han1, Ruiyi Zhai1, Bing Hu1
1Key Laboratory of Biotechnology and Bioresources Utilization of Ministry of Education, College of Life Science, Dalian Minzu University, Dalian 116600, China.
Foods (Basel, Switzerland)
|August 12, 2023
概括
合成和表征了八基-基尼化奇托寡糖化物 (OSA-COS). OSA-COS衍生物的自我组装减少,替代性增加,并表现出显著的抗真菌活性,使得稳定的阿斯丁封装.
科学领域:
- 生物材料科学 生物材料科学
- 聚合物化学 聚合物化学
- 食品科学 食品科学 食品科学
背景情况:
- 素寡糖化物 (COS) 是一种多功能生物聚合物,具有潜在的应用.
- 化学修饰可以增强特定用途的COS特性.
- 八基化引入了COS的两性质.
研究的目的:
- 为了合成和描述不同程度的替代性,八基-糖化基托寡糖化物 (OSA-COS).
- 评估溶液特性,自组装行为和OSA-COS的抗菌活性.
- 评估OSA-COS在乳液形成和阿斯塔克桑丁输送方面的潜力.
主要方法:
- 使用octenyl succinic 酸对奇托桑进行化学修饰.
- 使用1H NMR,FTIR和XRD进行表征.
- 评估表面张力,染料溶解,抗菌活性 (牛津杯法) 和乳液稳定性.
主要成果:
- 证实了octenyl succinylation,并实现了不同程度的替代.
- 在更高的替代水平下,OSA-COS表现出减少的自我组装.
- OSA-COS衍生品对Fusarium oxysporum表现出显著的抗真菌活性,并有可能在乳液中实现稳定的阿斯塔山丁封装.
结论:
- 八烯酸糖化有效地修改了奇托的寡糖特性.
- 作为一种抗真菌剂和乳化剂,OSA-COS显得有前途.
- 修改后的奇托适合封装和输送像阿斯塔克桑丁这样的疏水化合物.
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