虎牛奶对包裹和非包裹病毒的抗病毒特性:度和添加糖的影响
Alberto Tuñón-Molina1, Alba Cano-Vicent1, Ángel Serrano-Aroca1
1Biomaterials and Bioengineering Lab, Centro de Investigación Traslacional San Alberto Magno, Universidad Católica de Valencia San Vicente Mártir, 46001 Valencia, Spain.
International journal of molecular sciences
|August 12, 2023
概括
虎牛奶 (TNM) 显示出抗病毒潜力,可以对抗像SARS-CoV-2替代品这样的包裹病毒. 添加糖增强其广泛的抗病毒活性,即使对非包裹病毒.
科学领域:
- 病毒学 病毒学
- 自然产品化学 自然产品化学
背景情况:
- 随着COVID-19的流行,人们迫切需要新型抗菌剂.
- 自然化合物为抗病毒研究提供了可持续,安全和可生物降解的替代品.
研究的目的:
- 为了研究虎牛奶 (TNM) 的抗病毒性质,含糖和不含糖.
- 评估TNM对包裹病毒和非包裹病毒的疗效.
主要方法:
- 使用TNM在不同度下进行了抗病毒测试.
- 包裹式菌体phi6 (SARS-CoV-2代用物) 和非包裹式菌体MS2被用作模型病毒.
主要成果:
- TNM对包裹的细菌phi6表现出抗病毒活性.
- 没有观察到针对没有糖的非包裹细菌菌体MS2的抗病毒作用.
- 含糖的TNM (horchata) 呈现出对包裹病毒的增强抗病毒特性和对非包裹病毒的活性.
结论:
- 虎牛奶具有广泛的抗病毒特性,特别是在加糖时.
- 这种天然生物产品显示出对抗病毒感染和保护各种病毒性疾病的前景.
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