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Updated: Jul 19, 2025

Creation of a Knee Joint-on-a-Chip for Modeling Joint Diseases and Testing Drugs
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多核酸抑制炎症和刺激矩阵合成在一个基于体外细胞的骨关节炎模型中

Sree Samanvitha Kuppa1,2,3, Hyung-Keun Kim2,3, Ju-Yeon Kang2,3

  • 1Department of Biomedical Sciences, Chonnam National University Medical School, Hwasun 58128, Republic of Korea.

International journal of molecular sciences
|August 12, 2023
PubMed
概括

多核酸 (PN) 通过减少炎症和软骨退化,显示出治疗关节骨炎 (OA) 的潜力. 这项研究发现,PN抑制了关键的炎症途径,并在OA细胞模型中促进了软骨矩阵组件.

关键词:
冠状腺细胞 (chondrocytes) 是一种体内细胞.细胞外矩阵是细胞外矩阵.过度缩的过度缩是一个问题.这是一种炎症炎症炎症炎症.骨关节炎是一种关节炎.这是一种多核化物.

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