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Updated: Jul 19, 2025

Two- and Three-Dimensional Live Cell Imaging of DNA Damage Response Proteins
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Published on: September 28, 2012

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CSB 调节路径选择,以应对由坎普托西辛诱导的DNA复制压力

Nicole L Batenburg1, John R Walker1, Xu-Dong Zhu1

  • 1Department of Biology, McMaster University, Hamilton, ON L8S 4K1, Canada.

International journal of molecular sciences
|August 12, 2023
PubMed
概括

卡凯恩综合征B组 (CSB) 蛋白质管理着康普托西因 (CPT) 治疗后的DNA复制重启. 在高剂量的CPT中,CSB促进断裂诱导复制 (BIR),而其缺失允许其他途径,影响癌症治疗.

关键词:
卡凯恩综合征B组 (CSB) 的患者.另一个终端连接的替代连接.破裂诱导的复制.在Camptoothecin的营地里.不同类的末端连接.路径选择路径的选择.复制压力是复制的压力.

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