在老龄化LXRαβ淘汰赛小鼠中ERβ的损失导致大肠炎

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Xiaoyu Song1, Wanfu Wu1, Yubing Dai1

  • 1Center for Nuclear Receptors and Cell Signaling, Department of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA.

International journal of molecular sciences
|August 12, 2023
PubMed
概括

缺乏肝 X 受体 (LXRαβ-/-) 的老年小鼠表现出杯状细胞和粘素的减少,表明肠道屏障功能受损. 这种结肠表型与雌激素受体β (ERβ) 表达的丧失有关.

关键词:
大肠炎是一种大肠炎.雌激素受体β受体是什么炎症性肠道疾病 炎症性肠道疾病肝脏的X受体是一个X受体.丰满的积分 积分的积分

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