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Bone Remodeling

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.

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Updated: Jul 19, 2025

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

Published on: July 27, 2022

生物工程的近期进展基于含有氧酸盐的复合材料的骨再血管化

Yifan Niu¹, Lei Chen¹, Tianfu Wu^1,2

¹State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China.

International journal of molecular sciences

|August 12, 2023

概括

此摘要是机器生成的。

骨再生需要增强的血管化. 氧酸盐 (HA) 复合物显示出希望,最近的研究重点是改善HA特性,以改善骨愈合和骨组织工程 (BTE) 中的血管化.

关键词:

生物材料是一种生物材料.细胞和生长因子.氧帕提特是一种氧帕提特.结构性特征的结构性特征.血管化的血管化.

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科学领域:

生物材料科学生物材料科学
再生医学是一种再生医学.
整形外科的研究研究.

背景情况:

骨愈合通常受到瘤,创伤或炎症等条件的影响,需要外部干预来再生.
传统的骨移植方法有其局限性,导致需要先进的解决方案,如骨组织工程 (BTE).
血管化是成功修复和再生骨的关键因素.

研究的目的:

审查酸 (HA) 复合材料的最新进展,以提高骨再生中的血管化.
探索克服纯 HA 的局限性的策略,例如脆性和多孔性.

主要方法:

在过去五年内发表的HA复合研究的文献综述.
对HA属性的修改分析,包括材料组成,制造技术和生长因子集成.
检查涉及骨细胞促进血管化的共同培养技术.

主要成果:

酸 (HA) 具有出色的骨质导电性,生物活性和生物相容性,使其成为一种有价值的生物材料.
目前正在探索各种策略,以提高HA的机械性能和结构完整性,以改善应用.
研究表明,修改HA复合材料和采用先进的制造和细胞共同培养方法可以显著刺激血管化.

结论:

基于HA的复合材料是骨再生的有希望的途径,特别是当它们被设计为增强血管化时.
对HA复合材料的改造和制造技术的持续研究对于优化骨愈合结果至关重要.
增长因子和细胞组件的整合是实现工程骨结构中强大的血管化的关键.