狗牙周病中的基因组医学:系统性审查
Carolina Silva1,2, João Requicha1,2,3, Isabel Dias1,2,3,4,5
1Department of Veterinary Sciences, School of Agricultural and Veterinary Sciences (ECAV), University of Trás-os-Montes e Alto Douro (UTAD), Quinta de Prados, 5000-801 Vila Real, Portugal.
Animals : an open access journal from MDPI
|August 12, 2023
概括
基因组医学提供了对狗牙周病易感性的见解. 目前的研究突出了特定基因的变异,但需要更多的研究才能充分理解这种常见的狗病的遗传联系.
科学领域:
- 兽医基因组学 兽医基因组学
- 狗狗医学是一门医药.
- 牙周病研究 牙周病研究
背景情况:
- 基因组医学正在兽医实践中出现,使得对疾病易感性的基因分析成为可能.
- 牙周病在狗中非常普遍,但遗传因素仍未得到充分研究.
研究的目的:
- 系统地审查有关基因组医学和狗牙周病的文献.
- 确定研究的基因并评估它们在疾病发展中的潜在作用.
主要方法:
- 按照PRISMA 2020指南进行系统的文献审查.
- 分析了六项关于狗牙周病和遗传学的研究.
主要成果:
- 在interleukin-6,interleukin-10,interleukin-1,lactotransferrin,toll-like受体9和核因子-kappa B受体激活器基因中发现了遗传变异.
- 只有介质素-1和通类受体9基因的变异才有可能解释对牙周病的易感性.
结论:
- 关于狗牙周病遗传学的研究有限.
- 对基因多态变异的进一步研究对于了解疾病机制和易感性至关重要.
相关概念视频
Incomplete Dominance
22.8K
Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.
22.8K
Genomics
36.5K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
36.5K
Pedigree Analysis
84.5K
Overview
84.5K
Teeth
487
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
487


