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非食品前或益生菌使用与认知功能之间的关联:NHANES 2011-2014年的结果
Jingyi Chen1,2, Nian Yang1,2, Yilei Peng2
1Institute of Precision Medicine, The First Affiliated Hospital of Shantou University Medical College, Shantou 515041, China.
Nutrients
|August 12, 2023
概括
非食品益生菌和益生菌可以提高美国老年男性的认知功能. 这种食补充剂的使用与改善认知评分和减少男性损伤风险有关.
科学领域:
- 老年学是一门学科.
- 营养神经科学 营养神经科学
- 公共卫生 公共卫生
背景情况:
- 认知能力下降是老年人群的一个重大问题.
- 食补充剂,包括益生菌和益生菌,越来越多地探索认知益处.
研究的目的:
- 研究非食品益生菌/益生菌使用与美国老年人的认知功能之间的关联.
- 确定这些补充剂对认知表现的因果关系.
主要方法:
- 利用了2011-2014年国家健康和营养检查调查 (NHANES) 的数据.
- 采用多重线性回归,逻辑回归和倾向得分匹配 (PSM).
- 使用数字符号替换测试 (DSST),动物流利测试 (AFT),CERAD和复合Z-score评估认知功能.
主要成果:
- 非食品益生菌/益生菌使用与男性 (β=0.64) 的更高的综合认知功能 (sum.z) 有关.
- 这些补充剂对男性的认知障碍有保护作用 (OR=0.08).
- 倾向性得分匹配证实了男性认知功能的显著积极因果作用 (ATT=0.555,p < 0.05).
结论:
- 非食品益生菌或益生菌消费似乎是改善老年男性认知功能的有效策略.
- 研究结果表明,这些补充剂在减轻这一人口群体的认知衰退方面可能发挥作用.
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