披萨消费有助于改善类风湿关节炎的疾病活动吗?
Roberta De Vito1, Maria Parpinel2, Michela Carola Speciani3
1Department of Biostatistics, Data Science Initiative, Center for Computational Molecular Biology, Brown University, 121 South Main Street and 164 Angell Street, Providence, RI 02912, USA.
Nutrients
|August 12, 2023
概括
每周多吃一次披萨可能有利于类风湿性关节炎 (RA) 疾病活动. 这包括莫扎雷拉奶酪和橄油,可能减少RA症状和炎症.
科学领域:
- 类风湿病学 类风湿病学
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 类风湿性关节炎 (RA) 是一种慢性自身免疫性疾病,其特征是关节炎症.
- 饮食因素越来越多地被认为具有调节慢性疾病活动的潜力.
- 披萨消费对RA疾病活动的影响仍未得到研究.
研究的目的:
- 调查披萨及其成分与类风湿性关节炎 (RA) 疾病活性之间的关联.
主要方法:
- 一项涉及365名意大利RA参与者的横截面研究.
- 线性和后勤回归模型分析了披萨/食材消费和RA活动指标 (DAS28-CRP,SDAI) 之间的关系.
- 根据疾病的严重程度和持续时间进行了分层分析.
主要成果:
- 每周超过一次食用半个披萨与明显减少RA疾病活性有关 (DAS28-CRP和SDAI).
- 在患有更严重或长期RA的参与者中,有益影响更为明显.
- 莫扎雷拉奶酪和橄油的消费也显示出与降低RA疾病活动的积极关联,特别是在严重的病例中.
结论:
- 定期食用披萨,特别是带有莫扎雷拉奶酪和橄油的披萨,可能对类风湿性关节炎疾病的活性产生有益影响.
- 需要进一步的前性队列研究来证实这些发现并阐明潜在的机制.
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