成年人肥胖和骨矿物质密度之间的关联:来自全国调查分析的见解
Yang Jiao1, Juan Sun2, Yuanmeng Li3
1Department of Orthopedics, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Peking Union Medical College, Beijing 100730, China.
Nutrients
|August 12, 2023
概括
在成年人中,较高的体脂与较低的骨矿物质密度 (BMD) 有关. 总脂肪百分比 (TPF),安卓脂肪百分比 (APF),肌肉脂肪百分比 (GPF) 和内脏脂肪组织百分比 (VAT%) 显示了与BMD的负面关联.
科学领域:
- 内分泌学 在内分泌学.
- 骨生物学 骨生物学 骨生物学
- 公共卫生 公共卫生
背景情况:
- 已知肥胖和骨矿物质密度 (BMD) 密切相关.
- 了解这些关系对于骨健康管理至关重要.
研究的目的:
- 调查 BMD 与成年人各种脂肪度量之间的关联.
- 探索基于性别和年龄的潜在差异.
主要方法:
- 分析了来自NHANES (1999-2018) 的11,615名成年人 (18岁以上) 的数据.
- 研究了BMD和骨脂肪百分比 (GPF),安卓脂肪百分比 (APF),总脂肪百分比 (TPF),内脏脂肪组织百分比 (VAT%) 和总瘦质百分比 (TLM%) 之间的关联.
- 探索基于性别和年龄分层的差异.
主要成果:
- 在TPF,APF,GPF,VAT%和BMD之间发现了显著的负面关联.
- 总肌肉质量百分比 (TLM%) 显示与BMD的积极关联.
- 年龄和性别分层显示TPF,GPF和VAT%与BMD的持续负相关性,在年轻成年人中确定了特定的值,在男性和中年成年人中发现了APF的反转U形关系.
结论:
- 脂肪测量,特别是TPF,APF,GPF和VAT%,与成年人骨损伤有负面关联.
- 总瘦肉量与骨矿物质密度有积极的关联.
- 脂肪和BMD之间的关系是复杂的,并且随年龄和性别而异,突出了个性化骨健康策略的需要.
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