通过智能热比较/判断和控制来设计自动温度补偿系统,用于在高温腹腔内化学疗法 (HIPEC) 手术中稳定热治疗
Kicheol Yoon1,2, Sangyun Lee1,2, Tae-Hyeon Lee3
1Medical Devices R&D Center, Gachon University Gil Medical Center, 21, 774 Beon-gil, Namdong-daero, Namdong-gu, Incheon 21565, Republic of Korea.
Sensors (Basel, Switzerland)
|August 12, 2023
概括
这项研究引入了一个查看表 (LUT) 系统,以保持最佳的热量,以治疗癌症手术后残留的腹部瘤. 该系统通过自动调节换热器输出,确保快速,准确和安全的热疗法.
科学领域:
- 在瘤学瘤学.
- 生物医学工程 生物医学工程
- 手术技术 手术技术
背景情况:
- 卵巢和结直肠癌手术后的残留瘤是一个临床挑战.
- 在腹腔中使用高温药物的高热症是一种潜在的治疗方法.
- 药物循环期间的热损失降低了治疗的有效性.
研究的目的:
- 开发和评估一个系统,在高温治疗期间保持一致的治疗温度.
- 为了提高残留腹部瘤的热除的安全性和有效性.
主要方法:
- 使用查看表 (LUT) 系统来控制热交换器.
- 温度比较器 (TC) 监测药物温度,产生控制信号 (T).
- LUT调整了换热器输出以保持温度在41°C和43°C之间,响应时间为0.209μs.
主要成果:
- 通过动态调节加热或冷却,LUT系统成功地保持了目标温度范围 (41°C-43°C).
- 快速响应信号 (0.209微秒) 最小化了比较和判断错误.
- 该系统展示了自动调节温度的能力.
结论:
- 拟议的基于LUT的系统确保了残留腹部瘤的快速,准确和安全的热疗法.
- 自动温度调节可以提高处理性能和安全性.
- 这项技术有望在外科瘤学中应用.
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