仍然是一个:病毒是如何在细胞内和细胞之间移动的?
Mingshuo Xue1, Nathalie Arvy1, Sylvie German-Retana1
1Univ. Bordeaux, INRAE, UMR 1332 Biologie du fruit et Pathologie, Villenave d'Ornon Cedex, France.
Molecular plant pathology
|August 12, 2023
概括
植物RNA病毒的大型群体病毒会对作物造成重大损害. 本综述综合了当前关于这些病毒如何在植物细胞之间移动的知识,重点关注三个不同的传输机制.
科学领域:
- 植物病毒学 植物病毒学
- 分子生物学分子生物学
- 细胞生物学 细胞生物学
背景情况:
- 波提病毒是植物单链RNA病毒中最大的属,对全球实质性作物损失负责.
- 这些病毒利用宿主内膜系统进行复制和细胞对细胞的移动,通过等离子体 (PDs).
研究的目的:
- 提供关于病毒传输机制的全面审查.
- 整合有关病毒细胞间移动途径的现有数据.
- 为了突出病毒传输的复杂性和投机性方面.
主要方法:
- 文献综述和关于病毒运动的已发表数据的综合.
- 分析支持不同运输模式的实验证据.
- 讨论病毒蛋白和参与运动的宿主因素.
主要成果:
- 病毒的运动涉及使用宿主内膜系统的复杂途径.
- 提出了三种潜在的非排他性病毒传输机制:内膜系统利用,细胞外病毒囊泡和通过PDs直接的粒子/复合体传输.
- 介绍并讨论了支持这些模型的实验数据.
结论:
- 病毒的细胞间运动是多方面的,涉及多种潜在的策略.
- 需要进一步的研究,以充分阐明病毒传输机制的投机性方面.
- 了解这些途径对于开发控制病毒疾病的策略至关重要.
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