精液氧化应激对精子质量的影响:越南初步结果
Nguyen Dac Nguyen1,2, Minh Tam Le1,2, Hong Nhan Thi Dang1
1Center for Reproductive Endocrinology and Infertility, Hue University of Medicine and Pharmacy, Hue University, Vietnam.
The Journal of international medical research
|August 12, 2023
概括
氧化应激 (OS) 对男性生育能力产生负面影响,影响精子数量,运动性和DNA完整性. 测量氧化降低潜力 (ORP) 可以帮助评估不孕男性的精子质量.
科学领域:
- 生殖医学 生殖医学
- 安德罗学与人类学
- 生物化学 生物化学
背景情况:
- 氧化应激 (OS) 与男性不孕症有关.
- 氧化降低潜力 (ORP) 是OS的潜在生物标志物.
研究的目的:
- 为了研究OS (通过ORP测量) 和不育男性的精液分析参数之间的关系.
- 为评估精子质量建立一个ORP值.
主要方法:
- 对166名不育男性进行横截面研究.
- 对精液分析,精子DNA碎片化和ORP的评估.
- 对收集的数据进行统计分析.
主要成果:
- 患有OS的男性比没有OS的男性具有更高的DNA碎片化指数 (DFI).
- 精子度,数量,运动性和形态与ORP有负相关性.
- 鉴定了0.77mV/10^6精子/毫升的ORP值用于精子质量评估.
结论:
- 由ORP表示的OS,对精子数,运动性,形态和DFI产生不利影响.
- ORP可以作为评估不育男性精子质量的宝贵工具.
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