图像重新采样对基于放射学的人工智能在多中心前列腺MRI中的性能的影响
Jeroen Bleker1, Christian Roest1, Derya Yakar1,2
1Medical Imaging Center, Departments of Radiology, Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Journal of magnetic resonance imaging : JMRI
|August 12, 2023
概括
图像重新采样显著改善了使用MRI放射学在多个中心的前列腺癌检测. 优化的2D和3D重新采样策略提高了诊断性能,克服了数据异质性挑战.
科学领域:
- 放射学和人工智能在医学成像中的作用
- 前列腺癌的诊断方法 前列腺癌的诊断方法
- 多中心MRI研究 多中心MRI研究
背景情况:
- 前列腺癌 (PCa) 的单中心放射学模型对数据异质性表现出敏感性.
- 这种异质性限制了当前PCa放射学模型的诊断能力.
- 跨不同中心和扫描仪的标准化对于可靠的PCa检测至关重要.
研究的目的:
- 调查图像重新采样技术对放射学诊断性能的影响.
- 为了在前列腺MRI的多中心环境中评估这些影响.
- 确定最佳的重新采样策略,以改善PCa检测.
主要方法:
- 通过使用1.5T和3T扫描仪对来自9个中心的930名患者进行了回顾性分析.
- 使用T2加权成像 (T2W) 和扩散加权成像 (DWI) 数据.
- 使用各种重新采样方法 (分辨率,维度,插值) 创建了48个规范化的放射学数据集,以训练PCa检测模型.
主要成果:
- 最好的2D重新采样模型 (T2W:0.5mm Bspline,DWI:2mm最近邻居) 显著超过了2D基线 (AUC:0.77对比0.64).
- 最好的3D重新采样模型 (T2W:0.8毫米线性,DWI:2.5毫米最近邻) 显著超过了3D基线 (AUC:0.79对比0.67).
- 重复采样证明了对多中心放射学AI的诊断性能产生重大影响.
结论:
- 图像重新采样显著影响前列腺MRI中的多中心放射学AI的性能.
- 推的2D重新采样:同位素T2W在0.5毫米 (Bspline) 和DWI在2毫米 (最近的邻居).
- 推的3D放射学:同位素T2W在0.8mm (线性) 和DWI在2.5mm (最近的邻居).
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