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Updated: Jul 19, 2025

A Rapid Screening Workflow to Identify Potential Combination Therapy for GBM using Patient-Derived Glioma Stem Cells
05:29

A Rapid Screening Workflow to Identify Potential Combination Therapy for GBM using Patient-Derived Glioma Stem Cells

Published on: March 28, 2021

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针对质母细胞瘤核心漏洞的组合药物查揭示了药理上的协同作用

Jérémy Ariey-Bonnet1, Raphael Berges2, Marie-Pierre Montero1

  • 1Aix Marseille Université, Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Paoli Calmettes, Centre de Recherche en Cancérologie de Marseille (CRCM), Marseille, France.

EBioMedicine
|August 12, 2023
PubMed
概括

鉴定质母细胞瘤的协同药物组合是具有挑战性的. 这项研究发现,结合AURKA和BET抑制剂在临床前质母细胞瘤模型中显示出强效和低毒性.

关键词:
癌症的脆弱性 癌症的脆弱性药物组合查 药物组合查质母细胞瘤 (glioblastoma) 是一个药理学上的协同作用.目标是解散资产.

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