伦理委员会对多样性,公平性和包容性的审查:德尔菲共识声明
Laura G Meloney1, Hayat Ahmed1, Barbara E Bierer2
1Multi-Regional Clinical Trials Center of Brigham and Women's Hospital and Harvard, Division of Global Health Equity, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Med (New York, N.Y.)
|August 12, 2023
概括
在临床试验中确保多样化的群体是具有挑战性的. 这项研究通过Delphi过程制定了25条建议,以加强干预研究中的多样性和包容性.
科学领域:
- 临床研究 临床研究
- 医学伦理 医学伦理
- 健康 公平 卫生 公平
背景情况:
- 在干预试验中,多样化的人口代表性是一个持久的问题.
- 缺乏多样性可能会限制试验结果的概括性.
- 伦理考虑在确保公平参与研究方面至关重要.
研究的目的:
- 确定和巩固改善干预性临床研究多样性和包容性的建议.
- 肯定伦理委员会和机构在促进代表性试验方面的关键作用.
- 达成共识,为公平的研究制定可行的战略.
主要方法:
- 采用严格的德尔菲程序来收集专家的共识.
- 通过代反回合开发和完善建议.
- 在解决多样性和包容性障碍的战略上寻求共识.
主要成果:
- 在25项综合建议上达成共识.
- 建议分为四个关键主题,与试验进行相关.
- 伦理委员会和机构的中心作用得到了肯定.
结论:
- 已建立的建议为加强临床试验多样性的框架提供了框架.
- 实施这些建议可以促进更具包容性和公平性的干预研究.
- 持续关注伦理和机构实践对于具有代表性的研究群体至关重要.
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