持续口服免疫疗法的伦理含义 在患有埃索诺菲尔性食道炎后继续口服免疫疗法
Bridget E Wilson1, Ellen C Meltzer2, Benjamin L Wright1
1Division of Allergy, Asthma, and Clinical Immunology, Department of Medicine, Mayo Clinic, Scottsdale, Ariz; Section of Allergy and Immunology, Division of Pulmonology, Phoenix Children's Hospital, Phoenix, Ariz.
The journal of allergy and clinical immunology. In practice
|August 12, 2023
概括
用于治疗埃索诺菲尔性食道炎 (EoE) 的口服免疫疗法 (OIT) 存在道德上的挑战. 本综述探讨了EOE诊断后继续OIT的影响,强调共享决策.
科学领域:
- 过敏和免疫学 过敏和免疫学
- 胃肠病学 胃肠病学
- 医学伦理 医学伦理
背景情况:
- 性食道炎 (EoE) 是一种慢性过敏性炎症性疾病.
- 口服免疫疗法 (OIT) 传统上在EoE中是禁忌的,因为可能诱导这种情况.
- 最近的发现表明,即使在EoE开始后,OIT的延续也可能是可能的.
研究的目的:
- 分析在被诊断为EoE的患者中继续OIT的伦理影响.
- 检查OIT无敏化和OEE管理之间的冲突.
- 为过敏学家提供有关道德决策的指导.
主要方法:
- 审查关于 EoE 和 OIT 的现有文献.
- 应用核心医疗伦理原则 (公益,非有害,自主,正义).
- 讨论过敏学家面临的临床和伦理挑战.
主要成果:
- 在EoE诊断后继续OIT提出了复杂的伦理困境.
- 当伦理原则发生冲突时,共同决策至关重要.
- 关于EOE患者OIT的护理标准正在发展.
结论:
- 当考虑EOE诊断后继续OIT时,过敏学家必须应对道德挑战.
- 患者的自主权和共享决策至关重要.
- 需要进一步的研究和指导方针来管理EOE中的OIT.
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