关于在怀孕期间治疗乳腺癌 (PrBC) 的ESMO专家共识声明
S Loibl1, H A Azim2, T Bachelot3
1GBG c/o GBG Forschungs GmbH, Neu-Isenburg; Centre for Haematology and Oncology Bethanien, Frankfurt am Main, Frankfurt; Goethe University Frankfurt, Frankfurt am Main, Frankfurt, Germany.
概括
在怀孕期间治疗乳腺癌 (PrBC) 缺乏证据,需要专家的共识. 这个过程解决了有争议的PrBC管理主题,以改善患者护理.
科学领域:
- 在瘤学瘤学.
- 孕产妇和胎儿医学 孕产妇和胎儿医学
背景情况:
- 怀孕期间的乳腺癌 (PrBC) 是罕见的,由于临床试验的伦理限制,证据有限.
- 将成人乳腺癌 (BC) 治疗方案翻译为PrBC是复杂的,需要考虑母亲和胎儿的福祉.
- 对于PrBC管理的现有证据往往是有限的或矛盾的,导致有争议的方法.
研究的目的:
- 解决和提供专家共识在怀孕期间乳腺癌 (PrBC) 的管理中有争议的问题.
- 用专家对PrBC护理的见解来补充现有的基于证据的指南.
- 为治疗乳腺癌孕妇的临床医生提供信息决策的便利.
主要方法:
- 欧洲医学瘤学会 (ESMO) 在2022年召开了一个虚拟共识建设过程.
- 来自13个国家的24位顶尖专家组成的多学科小组参加了会议.
- 专家被分为四个工作组,每个工作组都专注于特定的PrBC管理主题,遵循ESMO标准操作程序.
主要成果:
- 达成共识的过程旨在就有争议的PrBC管理主题发表声明.
- 从一群多元化的国际专家中收集了洞察力.
- 结果旨在在缺乏或相互矛盾的证据的情况下为临床实践提供信息.
结论:
- 专家的共识对于在怀孕期间管理复杂的乳腺癌病例至关重要.
- 这个过程突出了需要进一步讨论的领域和对PrBC的潜在指导方针的改进.
- 开发的陈述为一个罕见但关键的临床场景提供了指导.
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