泰国治疗耐药抑郁症的患病率和经济负担
Jirada Prasartpornsirichoke1, Nuttorn Pityaratstian2,3, Chayanit Poolvoralaks4
1Department of Psychiatry, Faculty of Medicine, Chulalongkorn University, 1873 Rama IV Road, Pathumwan, Bangkok, 10330, Thailand. jirada.pr@chula.ac.th.
BMC public health
|August 12, 2023
概括
抗治疗性抑郁症 (TRD) 影响了泰国19.6%的大型抑郁症 (MDD) 患者. 与非TRD相比,TRD的经济成本要高得多,突出显示了相当大的财务负担.
科学领域:
- 精神病学是一个精神病学.
- 卫生经济学 卫生经济学
- 公共卫生 公共卫生
背景情况:
- 重度抑郁症 (MDD) 是一种普遍存在的心理健康状况.
- 耐治疗抑郁症 (TRD) 是MDD的一个亚型,需要进一步研究.
- 了解MDD和TRD的经济影响对于医疗保健政策至关重要.
研究的目的:
- 确定泰国公共三级医院中抗抑郁药治疗的MDD患者中TRD的患病率.
- 估计和比较与MDD,TRD和非TRD相关的经济成本.
- 确定区分TRD与非TRDMDD患者的因素.
主要方法:
- 一个综合的回顾性医疗记录审查和横截面调查.
- 包括500个抗抑郁药治疗的MDD患者和他们的无偿护理人员.
- 使用经过验证的问卷 (WPAI,CIQ,FEIS) 和统计分析 (奇方位,费舍尔的精确测试,独立的T测试).
主要成果:
- 在接受抗抑郁药治疗的MDD患者中,TRD患病率为19.6%.
- 与TRD相关的因素包括年轻年龄,早期发病,较低的BMI,自杀未遂和吸烟.
- 年化TRD的经济成本明显高 (276,059.97泰) 比非TRD (173,487.04泰).
结论:
- 与非TRD相比,TRD带来了巨大的经济负担,直接和间接成本更高.
- 调查结果强调了TRD对个人和医疗保健系统的重大财务影响.
- 对具有成本效益的TRD管理策略进行进一步研究是有必要的.
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