绿色植物中CaM/CML基因家族的演变和多样化
Qinghua Li1, Li Gao1, Feng Yu1
1State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, 430026, China.
Plant physiology and biochemistry : PPB
|August 13, 2023
概括
植物calmodulin (CaM) 和calmodulin-like (CML) 基因家族逐渐进化,CML数量通过重复增加,而CaM数量保持稳定. 这种扩张驱动了各种各样的工厂功能.
科学领域:
- 植物分子生物学 植物分子生物学
- 进化基因组学是进化的基因组学.
- 信号传递的.
背景情况:
- 卡尔莫杜林 (CaM) 和卡尔莫杜林类 (CML) 蛋白质是植物中重要的传感器.
- 它们的作用包括生长,发育和应激反应.
- 植物CaM/CML基因家族的进化历史尚不清楚.
研究的目的:
- 调查 CaM/CML 基因家族在不同植物系的起源和演变.
- 分析这些基因的扩张模式和功能多样化.
- 为了将基因家族大小与基因组特征相关联.
主要方法:
- 通过1000种植物 (1KP) 项目和其他测序基因组,在各种植物物种中识别CaM和CML基因.
- 对比基因组学和遗传学分析.
- 对基因重复事件和EF手域保护的分析.
- 对CaM和CML基因的表达概况.
主要成果:
- 在绿色植物中发现了超过2133个CaM和23094个CML基因.
- CML基因家族的大小与基因组大小和总基因数相关.
- ML基因主要通过细分重复从藻类扩展到血管苗; CaM数量保持稳定 (2-3).
- CaM起源于绿藻,而CML早在恐龙虫中出现.
- CaM EF手域是保留的;CML域是多样化的.
- 较高的CaM表达表明基本角色,而较低的CML表达表明功能多样化.
结论:
- 由于基因重复,CaM/CML基因家族经历了显著的进化扩张,特别是CML亚家族.
- 在植物生物学中,CaM的保护性和CML的多样性有助于发挥不同的和必不可少的作用.
- 了解CaM/CML演变,可以了解它们的分子功能和植物适应.
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